Clinical Application of Mesenchymal Stem Cells in Orthopaedics and Traumatology in Daily Practice
Mesenchymal stem cells (MSCs) have been widely used in preclinical and clinical orthopaedic and traumatology studies (1). Compared to other cell therapies, MSCs have a variety of characteristics, such as a lower risk of teratoma than pluripotent stem cells, stemness potency, targeted therapy through chemo-attraction, ease of isolation, and rapid proliferation (2). However, the application from bench to bedside requires a standardized procedure for its administration (1).
Source: ScienceDirect
Current and Emerging Therapies for Knee Osteoarthritis: From Conventional Approaches to Machine Learning and Stem Cell Innovations
Osteoarthritis is characterized by cartilage degradation and joint distortion. The most prevalent version of osteoarthritis, knee osteoarthritis (KOA), affects millions, acting as a leading cause of disability.
Source: ScienceDirect
6 safe exercises for a herniated disk
Healthcare professionals may recommend a physical therapy program for people with a herniated disk that includes gentle exercises, stretches, and movements to help relieve pain and improve mobility. This article looks at some exercises that can help relieve pain, speed recovery, and prevent a herniated disk from recurring.
Source: Medical News Today
What Is Spinal Stenosis?
Spinal stenosis involves a narrowing of the spinal canal, leading to compression of the spinal cord or nerves, commonly due to osteoarthritis. This condition (commonly caused by osteoarthritis) can cause pain and numbness in various body parts, with treatment options available to manage symptoms effectively.
Source: Verywell Health
Lumbar Traction: Uses, Procedure, Side Effects, and More
Lumbar traction is sometimes used to ease low back pain, but studies suggest it doesn't offer more relief than exercise alone. For better outcomes, postural correction and targeted exercises are recommended.
Source: Verywell Health
Understanding Sacroiliac (SI) Joint Pain: Causes, Treatment, and When Surgery Helps
Lower back and hip pain are common-but not all pain comes from the spine. The sacroiliac (SI) joint is a frequent and often overlooked source. Because this joint behaves differently from others in the body, SI joint problems can be difficult to recognize, but very treatable once properly diagnosed.
Source: Spine Health Foundation
Biological Treatment in Meniscus Injury
Meniscal injuries, common in sports, often cause knee pain and instability. The meniscus plays a key role in pressure distribution and joint stability, making its repair essential. Treatments range from conservative approaches to surgical interventions, with growing interest in biological factors such as growth factors, mesenchymal stem cells, platelet-rich plasma, fibrin clot, and tenocyte to enhance healing. This review compares the effects of these biological agents in meniscal repair, examining their mechanisms, limitations, and clinical outcomes.
Biologics for bone regeneration: advances in cell, protein, gene, and mRNA therapies
Bone fractures represent a significant global healthcare burden. Although fractures typically heal on their own, some fail to regenerate properly, leading to nonunion, a condition that causes prolonged disability, morbidity, and mortality. Biologic therapies have emerged as promising tools to enhance bone regeneration by leveraging the body's natural healing processes. This review explores the critical role of conventional and emerging biologics in fracture healing.
Source: Nature
Surging spinal and joint disorders supporting orthobiologics demand
Orthobiologics play a critical role in the treatment of spinal disorders, joint degeneration, fractures, and sports-related injuries. As healthcare systems increasingly focus on regenerative and minimally invasive treatment approaches, orthobiologics are gaining widespread acceptance across hospitals, orthopaedic clinics, and ambulatory care settings.
Source: Spinal Surgery News
Excess Weight Increases Risk Of Low Back Pain, Researchers Find
Did holiday treats add a few extra pounds to your frame? If so, your risk for low back pain might have increased, as well, a new study says.
Source: HealthDay
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