Biological Treatment in Meniscus Injury
Meniscal injuries, common in sports, often cause knee pain and instability. The meniscus plays a key role in pressure distribution and joint stability, making its repair essential. Treatments range from conservative approaches to surgical interventions, with growing interest in biological factors such as growth factors, mesenchymal stem cells, platelet-rich plasma, fibrin clot, and tenocyte to enhance healing. This review compares the effects of these biological agents in meniscal repair, examining their mechanisms, limitations, and clinical outcomes.
Biologics for bone regeneration: advances in cell, protein, gene, and mRNA therapies
Bone fractures represent a significant global healthcare burden. Although fractures typically heal on their own, some fail to regenerate properly, leading to nonunion, a condition that causes prolonged disability, morbidity, and mortality. Biologic therapies have emerged as promising tools to enhance bone regeneration by leveraging the body's natural healing processes. This review explores the critical role of conventional and emerging biologics in fracture healing.
Source: Nature
Surging spinal and joint disorders supporting orthobiologics demand
Orthobiologics play a critical role in the treatment of spinal disorders, joint degeneration, fractures, and sports-related injuries. As healthcare systems increasingly focus on regenerative and minimally invasive treatment approaches, orthobiologics are gaining widespread acceptance across hospitals, orthopaedic clinics, and ambulatory care settings.
Source: Spinal Surgery News
Excess Weight Increases Risk Of Low Back Pain, Researchers Find
Did holiday treats add a few extra pounds to your frame? If so, your risk for low back pain might have increased, as well, a new study says.
Source: HealthDay
From Scalpels to Stem Cells: How Regenerative Medicine Is Changing Spine Surgery
For much of modern history, orthopedic surgery has relied on precision, hardware, and long recoveries. The rhythm was familiar: a problem in the spine or joint would lead to imaging, diagnosis, and ultimately surgery. But in the last decade, a quiet revolution has begun. Instead of opening the body to fix what is broken, physicians like Dr. Michael Gerling are learning how to help the body repair itself.
Source: OrthoSpineNews
Stem Cell Pain Sponge Soaks up Osteoarthritis Joint Pain and Protects Cartilage
SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain while protecting joint tissue. Instead of blocking pain pathways, SN101 uses lab-grown nociceptors that act like sponges, soaking up inflammatory pain factors without sending pain signals. These cells also release regenerative molecules, offering disease-modifying potential that stands apart from traditional corticosteroids and single-target drugs like Nav1.8 inhibitors.
Source: ScienceDaily
Acute Low Back Pain Guideline on the Way
A clinical practice guideline for the Assessment and Treatment of Acute Low Back Pain is being developed by a multidisciplinary guideline development group (GDG), including the American Academy of Pain Medicine (AAPM).
Source: MedCentral
12 Exercises to Do After Low Back Surgery
Recovering from low back surgery can be challenging, but with the right exercises, you can regain strength and stability. Here are 12 exercises recommended by physical therapists to enhance your recovery following a lumbar laminectomy and discectomy.
Source: Verywell Health
What Does Spinal Cord Compression Feel Like?
Spinal cord compression-also called cervical spondylotic myelopathy (CSM)- is caused by any condition that puts pressure on the spinal cord. Symptoms may develop suddenly or gradually and may include pain or stiffness in the neck or back, balance issues, or a burning pain in the arms or legs.
Source: Verywell Health
How do you get rid of a lower back spasm?
Lower back spasms can be painful, but they are treatable. Certain remedies, stretches, and lifestyle changes can help reduce or get rid of back spasms.
Source: Medical News Today
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